Modifying Enzymes
Cayman Chemical N-Oleoyl ValIn 25mg
An endogenous N-acyl amine; antagonist at TRPV3; increases after acute lung injury in mouse lung tissue
Medchemexpress LLC Tlr4-in-c34-c2-cooh | 1159408-54-4 | MFCD30802159 | 99.9% | 447.43 g/mol | C19H29NO11 | 100 MG
TLR4-IN-C34-C2-COOH is a small-molecule PROTAC linker that incorporates a TLR4 inhibitor moiety and is supplied for research use to support studies of TLR4 biology and probe or degrader synthesis. It has documented activity inhibiting TLR4 in enterocytes and macrophages and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.
- High purity of 99.9%.
- Molecular formula C19H29NO11; molecular weight 447.43 g/mol.
- Soluble in DMSO and water at 100 mg/mL with ultrasonic assistance.
- Formulation examples yield ≥ 2.5 mg/mL (5.59 mM) in common in vivo vehicles.
- Available in multiple pack sizes including 100 mg.
- Intended for research use only; not for human or veterinary use.
STEMCELL Technologies DNase I, ACF, Size: 500000 U
Deoxyribonuclease I (DNase I), Animal Component-Free (ACF) is obtained from cultures free of animal-derived materials and purified by chromatography. DNase I is an endonuclease consisting of a single glycosylated polypeptide chain with two disulfide bonds. DNase is often included in tissue dissociation protocols to digest DNA that has leaked into the dissociation medium as a result of cell damage. DNase I, ACF preferentially cleaves phosphodiester linkages adjacent to pyrimidine nucleotides in both single- and double-stranded DNA, yielding polynucleotides with 5’-phosphate and 3’-hydroxyl groups (Bernardi et al.). DNase I has been used for the digestion of human tissues such as microglia (Klegeris & McGeer), cartilage (Dunham & Koch), colon (Fukushima & Fiocchi), epithelium l (Fukushima & Fiocchi), liver (Vatakis et al.), lung (Fujino et al.), neural (Fuja et al.), and stem cells (Kusuma et al.).
![Chem-Impex International, Inc. Proteinase K from Tritirachium album [EC 3.4.21.64] | 39450-01-6 | MFCD00132129 | 1G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Chem-Impex International, Inc. Proteinase K from Tritirachium album [EC 3.4.21.64] | 39450-01-6 | MFCD00132129 | 1G
Proteinase K from Tritirachium album [EC 3.4.21.64], 39450-01-6, MFCD00132129, 1G
Meridian Life Science Gly-Free RNase H -HC, 20UL
Glycerol-Free RNase H (HC) is a high concentration (50 U/uL) RNA-specific endonuclease that hydrolyzes the phosphodiester bonds of RNA, when hybridized to DNA and produces 5´ phosphate-terminated oligoribonucleotides and single-stranded DNA. It does not hydrolyze the phosphodiester bonds within single-stranded and double-stranded DNA and RNA. Glycerol-Free RNase H (HC) has been optimized to deliver excellent, stable performance without glycerol, allowing you to deliver reliable results with the added capability for lyophilization. This gives you the flexibility to confidently store reaction mixtures at ambient temperature or produce diagnostic assays that rely on miniaturized reaction components.
Aldevron Eureca-V Nuclease, 1mg
1mg dispense of Eureca-V Nuclease. CRISPR protein, Eureca-V™ Nuclease is the most recent addition to our catalog. It is based on the proprietary MAD7 nuclease developed by Inscripta. Aldevron and Inscripta have partnered to make this protein broadly available to the therapeutic, diagnostic, and agricultural research markets.Eureca-V is categorized as a Class 2, Type V CRISPR-Cas nuclease. It shares key features common to this family of CRISPR nucleases, including:
•Targets broad array of T-rich PAM domains (YTTV preferred, TTTN functions)
•Requires a single crRNA to cut target DNA sequence
•Staggered double-strand break at cut site creates 5’ overhangs
This product is subject to the following: Limited Use Label License
Meridian Life Science Lyo-Ready T4 Ligase Buffer, 10ML
Lyo-Ready T4 Ligase Buffer, 5x is a glycerol-free ligation reaction buffer containing ATP and lyo-excipients. It is designed to be used with Glycerol-Free T4 DNA Ligase (HC) (MDX200) to create a wet mix or a lyophilized, ambient-temperature stable mix for the ligation of cohesive blunt ended DNA.
ABclonal Technology T7 Exonuclease
T7 Exonuclease is a double-stranded DNA-specific exonuclease that degrades linear or nicked double-stranded DNA in the 5′to 3′direction. The enzyme does not digest supercoiled dsDNA.
INTACT GENOMICS INC Cas9 Nuclease 400 µg
Intact Genomics Cas9 Nuclease is the purified recombinant Streptococcus pyogenes Cas9 enzyme containing a nuclear localization signal (NLS) at the C-terminal for targeting to the nucleus. This enzyme is designed to perform CRISPR/Cas9-mediated genome editing (1, 2). The physical purity of this enzyme is ≥98% as assessed by SDS-PAGE with Coomassie blue staining. Product Source:E. coli BL21 (DE3) strain expressing a Cas9 gene from Streptococcus pyogenes with an N-terminal 6xHis tag and C-terminal SV40 nuclear localization signal (NLS).Product Includes: Cas9 Nuclease 10x Cas9 Nuclease Reaction Buffer
ABclonal Technology DNase I , RNase-free (5,000 U/mL)
DNase I （deoxyribonuclease, RNase-free ） is an endonuclease that nonspecifically cleaves DNA to release di-, tri-, and oligonucleotide products with 5phosphorylated and 3?-hydroxylated ends. The activity of DNase I depends on Ca2+ and also be activated bydivalent metal ions Mg2+, Mn2+, etc.DNase I act on various DNAs such as single and double-stranded DNA, RNA:DNA hybrids.
Med Vet International Omeprazole Delayed Release Capsules, 40mg, 100ct.
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Omeprazole is a proton pump inhibitor that helps decrease the amount of acid produced in the stomach.
Sino Biological SuperNuclease
SuperNuclease is a recombined Serratia marcescens’ extracellular endonuclease. The sequence is same with Benzonase (Benzonase is a trademark of Merck KGaA, Darmstadt, Germany).
C LECTA GMBH DENARASE High Salt 500 kU Enzymes & Nucleases
The salt-tolerant enzyme cleaves all forms of DNA and RNA and enables a simpler more efficient downstream process at salt concentrations above 150 mM - Purity 98% - Activity 250 U/ul - Formulation buffered aqueous glycerol solution - Storage Temperature -20C - Produced under ISO 9001 standard- Manufactured without the use of antibiotics Triton X-100 and raw materials of animal origin- - Net price excluding VAT and shipment costs
c-LEcta will ship the Products, as the case may be and at its sole discretion, either directly from Leipzig, Germany, or from c-LEcta’s third party service provider in the US. In the latter case, c-LEcta has already incurred all costs and fees related to the import of the Products into the US. Such costs and fees will be passed on by c-LEcta to the customer without any deductions or surcharges, if the Products are shipped from c-LEcta’s third party service provider in the US to the customer